Pharmacology in Pediatric Oncology

Clinical pharmacology is a swift altering field. It is necessary for cancer care providers and oncologists to keep existing in the developments of pharmacokinetics, clinical trial design and pharmacogenomics. Cancer pharmacology comprise the study of the initial mechanisms of signal transduction accompanying with cell proliferation and apoptosis, the design and discovery of new drugs, the mechanisms of action of anti-neoplastic agents, initial mechanisms of DNA damage tolerance and DNA repair and the development of innovative approaches for gene therapy. Other areas of Cancer Pharmacology research comprise of free radical generation, molecular mechanisms of antioxidant regulation and detoxification, investigations on interleukin therapy, aberrations in the mechanisms of apoptosis linked with tumoral growth. The role of growth factors in the development of hematopoietic and solid tumors is being studied

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